一、学习工作经历

2007.09-2011.06，哈尔滨学院，生物科学专业，学士

2011.09-2013.06，华中科技大学，生物工程专业，硕士

2014.09-2022.09，华中科技大学大学，微生物学专业，博士

2022.11-至今，新乡学院工程学院，讲师

二、主持科研项目

氯化胆碱基深共晶溶液在木质纤维素预处理工艺中的应用研究（24A180023），河南省高校重点研究项目，3万元，2024.1—2025.12，主持人。

三、代表性论文、专利、论著等：

1.He, Y., Li, K., Wang, J., Xu, L., Yan, J., Yang, M., Yan, Y.A Novel Strategy for Biodiesel Production by Combination of Liquid Lipase, Deep Eutectic Solvent and Ultrasonic-assistance in Scaled-up Reactor: Optimization and Kinetics. Journal of Cleaner Production, 2022, 372, 133740.

2.He, Y., Li, K., Bo, G., Wang, J., Xu, L., Yan, J., Yang, M., Yan, Y.Enhancing biodiesel production via liquid Yarrowia lipolytica lipase 2 in deep eutectic solvents. Fuel, 2022, 316, 123342.

3. Murillo, G.,He, Y., Yan, Y., Sun, J., Bartocci, P., Ali, S.S., Fantozzi, F.Scaled-up biodiesel synthesis from Chinese Tallow Kernel oil catalyzed by Burkholderia cepacia lipase through ultrasonic assisted technology: A non-edible and alternative source of bioenergy. Ultrasonics Sonochemistry, 2019, 58, 104658.

4. Wang, J., Li, K.,He, Y., Liu, X., Wang, P., Xu, L., Yan, J., Yan, Y.Bi-enzyme directed self-assembled system toward biomimetic synthesis of fatty acid hydroperoxides like soybean. Composites Part B: Engineering, 2021, 222,109091.

5. Yang, X., Zhang, Y., Pang, H., Yuan, S., Wang, X., Hu, Z., Zhou, Q.,He, Y., Yan, Y., Xu, L.Codisplay of rhizopus oryzae and candida rugosa lipases for biodiesel production, Catalysts, 2021, 11 (4), 421.

6. Zhao, Y., Yan, Y., Xie, L., Wang, L.,He, Y., Wan, X., Xue, Q.Long-term environmental exposure to microcystins increases the risk of nonalcoholic fatty liver disease in humans: A combined fisher-based investigation and murine model study. Environment International, 2020, 138, 105648.

7. Wang, J., Li, K.,He, Y., Wang, Y., Yan, J., Xu, L., Han, X., Yan, Y.Lipase Immobilized on a Novel Rigid-Flexible Dendrimer-Grafted Hierarchically Porous Magnetic Microspheres for Effective Resolution of (R, S)-1-Phenylethanol, ACS Applied Materials and Interfaces,2020, 12 (4): 4906-4916.

8. Xu, L., Xiao, X., Wang, F.,He, Y., Yang, X., Hu, J., Feng, Z., Yan, Y. Surface-Displayed Thermostable Candida rugosa Lipase 1 for Docosahexaenoic Acid Enrichment. Applied Biochemistry and Biotechnology, 2020, 190 (1): 218-231.

9. Wang, J., Li, K.,He, Y., Wang, Y., Han, X., Yan, Y. Enhanced performance of lipase immobilized onto Co2+-chelated magnetic nanoparticles and its application in biodiesel production. Fuel, 2019, 255,115794.

10. Murillo, G., Ali, S.S., Sun, J., Yan, Y., Bartocci, P., El-Zawawy, N., Azab, M.,He, Y., Fantozzi, F. Ultrasonic emulsification assisted immobilized Burkholderia cepacia lipase catalyzed transesterification of soybean oil for biodiesel production in a novel reactor design. Renewable Energy, 2019, 135, 1025-1034.

11. Yang, K., Li, F., Qiao, Y., Zhou, Q., Hu, Z.,He, Y., Yan, Y., Xu, L., Madzak, C., Yan, J. Design of a New Multienzyme Complex Synthesis System Based on Yarrowia lipolytica Simultaneously Secreted and Surface Displayed Fusion Proteins for Sustainable Production of Fatty Acid-Derived Hydrocarbons. ACS Sustainable Chemistry and Engineering,2018, 6 (12), 17035-17043.

12. Li, K., Wang, J.,He, Y., Cui, G., Abdulrazaq, M.A., Yan, Y. Enhancing enzyme activity and enantioselectivity of Burkholderia cepacia lipase via immobilization on melamine-glutaraldehyde dendrimer modified magnetic nanoparticles. Chemical Engineering Journal, 2018, 351, 258-268.

13. Li, K., Wang, J.,He, Y., Abdulrazaq, M.A., Yan, Y. Carbon nanotube-lipase hybrid nanoflowers with enhanced enzyme activity and enantioselectivity. Journal of Biotechnology, 2018, 281, 87-98.

14. Murillo, G., Sun, J., Ali, S.S., Yan, Y., Bartocci, P.,He, Y.Evaluation of the kinematic viscosity in biodiesel production with waste vegetable oil, ultrasonic irradiation and enzymatic catalysis: A comparative study in two-reactors. Fuel, 2018, 227, 448-456.

15. Li, K., Fan, Y.,He, Y., Zeng, L., Han, X., Yan, Y. Burkholderia cepacia lipase immobilized on heterofunctional magnetic nanoparticles and its application in biodiesel synthesis. Scientific Reports,2017, 7 (1), 16473.

16. Zeng, L.,He, Y., Jiao, L., Li, K., Yan, Y. Preparation of Biodiesel with Liquid Synergetic Lipases from Rapeseed Oil Deodorizer Distillate. Applied Biochemistry and Biotechnology, 2017, 183 (3), 778-791.

17. Zhao, Y., Cao, Q.,He, Y., Xue, Q., Xie, L., Yan, Y. Impairment of endoplasmic reticulum is involved in Β-cell dysfunction induced by microcystin-LR. Environmental Pollution, 2017, 223, 587-594.

18. Yang, W.,He, Y., Xu, L., Zhang, H., Yan, Y. A new extracellular thermo-solvent-stable lipase from Burkholderia ubonensis SL-4: Identification, characterization and application for biodiesel production.Journal of Molecular Catalysis B: Enzymatic,2016, 126, 76-89.

19.库流鹏,贺珧珈,姚杰,曹海,闫云君.无溶剂体系中酶法催化微藻油脂乙酯化制备生物柴油工艺研究[J].应用化工,2015,44(05):830-834+837.

20.李锚,贺珧珈,徐莉,张后今,闫云君.具协同催化效应的毕赤酵母全细胞催化生物柴油制备[J].应用化工,2014,43(08):1403-1407.

四、教科研成果：博士，讲师，研究方向为农林生物质高值化技术。主持河南省高校重点研究项目1项，参与多项国家自然科学基金和省级科研项目，发表科研论文20余篇，其中第一及共一作者发表SCI一区论文3篇。